Molecular signatures may aid fight against pediatric liver disease
Updated: 2010-06-30 19:51:04
Home About Our Bloggers Science by Email Science Store Twitter Subscribe Molecular signatures may aid fight against pediatric liver disease by bjs on June 30, 2010 Researchers have identified a set of molecular signatures” for biliary atresia the most common diagnosis leading to liver transplant in children that can help identify the progression of disease at diagnosis and predict clinical . outcomes The Cincinnati Children’s Hospital Medical Center scientists found that using traditional methods to analyze liver biopsies , only 14 of 47 infants with biliary atresia could be identified as having either inflammation or fibrosis development of excess fibrous connective tissue By examining the expression of the entire genome in the liver , the researchers developed a molecular signature that